Mercy Hospital St. Louis is a 715-bed academic teaching hospital located at 615 S. New Ballas Road in west St. Louis County, Missouri, serving the St. Louis region for more than 150 years with nationally recognized care across trauma, oncology, cardiovascular services, women’s health, pediatrics, burn care, stroke care, and dozens of additional specialties. The hospital operates St. Louis County’s only Level 1 Trauma Center, the only verified adult and pediatric burn center in Missouri, and a Level IV NICU offering the most advanced neonatal care in St. Louis County. Patients seeking specialty-level care will find that the same commitment to patient outcomes shown at Dr. Gina Sims’ practice is mirrored in Mercy Hospital St. Louis’s nationally benchmarked standards of care.
Overview of Mercy Hospital St. Louis
Mercy Hospital St. Louis is a 715-staffed-bed, fully accredited teaching hospital in Creve Coeur, Missouri, handling 101,387 emergency department visits, 44,138 total surgeries, 8,178 births, and 46,711 inpatient discharges annually as of fiscal year 2025.
The hospital campus encompasses the Heart and Vascular Hospital, David C. Pratt Cancer Center, Mercy Children’s Hospital, Mercy Birthplace, a Surgery Center with 29 operating rooms, and the Mercy Center for Performance Medicine and Specialty Care, one of the largest ambulatory surgery centers in the country. Over 1,362 total providers serve patients across more than 55 services and specialties.
U.S. News and World Report ranks Mercy Hospital St. Louis as the second-best hospital in Missouri and second-best in St. Louis, with high-performing designations across 21 adult procedures and conditions spanning cancer, cardiology, orthopedics, and more. According to Newsweek, the hospital also ranks among the Top 50 Best Hospitals in the nation.
| Detail | Information |
|---|---|
| Address | 615 S. New Ballas Road, St. Louis, MO 63141 |
| Phone | (314) 251-6000 |
| Hours | Open 24 hours, 7 days a week |
| Staffed Beds | 715 (FY2025) |
| Hospital Type | Academic Teaching Hospital |
| Trauma Level | Level 1 (highest) — only one in St. Louis County |
| Stroke Designation | Level 1 Stroke Center; Joint Commission Advanced Thrombectomy Capable |
| Burn Center | Only verified adult and pediatric burn center in Missouri |
| NICU Level | Level IV (highest) — most advanced in St. Louis County |
| U.S. News Ranking | #2 in Missouri, #2 in St. Louis; High Performing in 21 procedures |
Trauma Center and Emergency Services
Mercy Hospital St. Louis operates St. Louis County’s only Level 1 Trauma Center, providing the highest level of emergency and trauma care around the clock for patients from St. Louis County, St. Charles County, and surrounding areas.
The emergency department handled 101,387 visits in fiscal year 2025. Level 1 designation, awarded by the American College of Surgeons, confirms that the facility maintains the full spectrum of trauma surgery, anesthesia, and specialist coverage 24 hours a day, 365 days a year, meeting the highest standards for immediate care of life-threatening injuries.
Mercy also offers ERAdvisor, a real-time mobile tool that gives patients and families live updates about wait times and ER visit status directly on their phones.
Burn Center
The Burn Center at Mercy Hospital St. Louis is the only American Burn Association and American College of Surgeons verified center in Missouri for both adult and pediatric burn care, providing acute treatment and long-term reconstructive services.
The center treats severe burns caused by fire, extreme heat, electricity, friction, and chemicals, using a team of specially trained burn surgeons and nurses. After initial stabilization, a long-term recovery plan is coordinated with primary physicians and specialists across the Mercy network, including inpatient rehabilitation services for patients recovering from major trauma.
Stroke Center
Mercy Hospital St. Louis’s Stroke Center holds Level 1 designation and is certified by The Joint Commission as an Advanced Thrombectomy Capable Stroke Center, with 24/7 access to neurology specialists and life-saving stroke intervention.
The center also carries Level II Thrombectomy-Capable Stroke Center designation from the Missouri Department of Health and Senior Services. The hospital earned the American Heart Association’s Get With the Guidelines Gold Plus, Target: Honor Roll Elite Plus, Advanced Therapy, and Type 2 Diabetes Honor Roll achievement award, reflecting consistent excellence across stroke and cardiac care quality metrics.
Heart and Vascular Hospital
The Heart and Vascular Hospital at Mercy Hospital St. Louis brings all cardiovascular and emergency services together in a single facility, offering comprehensive heart care recognized by the American College of Cardiology in the 2025 U.S. News and World Report Best Hospitals issue.
The hospital was the first in Missouri to offer Hybrid Coronary Revascularization for bypass surgery, and it holds 2-Star TAVR designation for transcatheter aortic valve replacement. The Intersocietal Accreditation Commission has accredited the facility for adult and pediatric echocardiography and vascular testing, and the Society of Chest Pain Centers has recognized the hospital for heart failure care.
Cancer Care
The David C. Pratt Cancer Center at Mercy Hospital St. Louis provides comprehensive outpatient cancer care across 100,000 square feet of diagnostic and research capability, holding American College of Surgeons Commission on Cancer accreditation with commendations.
Cancer treatment technologies include CyberKnife M6, da Vinci Xi robotic surgery, TomoTherapy Hi-Art System, Stereotactic Radiosurgery and Body Radiotherapy, and Proton Beam Therapy for precision radiation delivery. The hospital is rated High Performing by U.S. News in colon cancer surgery, gynecological cancer surgery, leukemia, lymphoma and myeloma, lung cancer surgery, and prostate cancer surgery. The AI platform Aidoc and the aiOS system helps care teams prioritize urgent imaging cases across the Mercy network at no additional cost to patients.
Women’s Health and Maternity Services
Mercy Hospital St. Louis delivers more babies than any other St. Louis hospital, with one in three babies born in St. Louis arriving at Mercy, and is the first Missouri hospital recognized by J.D. Power and Associates for Outstanding Patient Experience in maternity care.
The hospital recorded 8,178 births in fiscal year 2025. Maternity options include Mercy Birthplace with whirlpool tubs and low-intervention birth suites, a Midwifery Birthing Center for natural childbirth, the Level IV NICU for the most advanced neonatal care in St. Louis County, and the Maternal and Fetal Health Center for high-risk pregnancies. The hospital is designated an AAGL Center of Excellence in Minimally Invasive Gynecology and a Center of Excellence for OB Anesthesia by the Society for Obstetric Anesthesia and Perinatology.
Children’s Hospital and Pediatric Services
Mercy Children’s Hospital St. Louis provides over 165 pediatric beds including a Pediatric Intensive Care Unit, the only PICU in St. Louis County, handling 22,000 pediatric emergency visits annually and staffing 175 pediatric providers including 80 fellowship-trained specialists.
The Children’s Hospital performs over 4,200 pediatric surgery cases annually and maintains 24-hour in-house neonatology and pediatric hospitalist coverage. More than 1,340 NICU admissions are processed each year, with the hospital offering active child life programs in both the hospital and the pediatric emergency department.
Technology and Innovation
Mercy Hospital St. Louis holds HIMSS Stage 7 validation, placing it among the most technologically advanced hospitals in the country, and was one of only nine health systems chosen to develop the first commercially available ambient AI solution for nurses within Microsoft Dragon Copilot.
The hospital uses the Aidoc aiOS platform for AI-assisted imaging prioritization, Mazor X robotic spinal surgery, and 3D tomosynthesis mammography. Mercy Virtual provides 24-hour remote ICU monitoring across the health system. The hospital’s EPIC-based electronic health record delivers a single unified patient record across all care settings.
History of Mercy Hospital St. Louis
Mercy Hospital St. Louis traces its founding to 1856, when the Sisters of Mercy arrived in St. Louis, and to 1871, when they converted a school building into a 25-bed hospital known as St. John’s Hospital, one of the first hospitals for women and children in the region.
By 1874 the hospital expanded to serve all patients as a general facility. The current west St. Louis County campus opened in 1963, replacing the original Euclid Avenue location as the city’s population expanded westward. The campus has grown continuously since, with the David C. Pratt Cancer Center opening in 2003, the Heart and Vascular Hospital in 2006, the Children’s Hospital expansion in 2010, the hospital’s rebranding to Mercy Hospital St. Louis in 2011, and the Mercy Center for Performance Medicine and Specialty Care opening in 2023. The original site was once an apple orchard, a detail Mercy’s own historical records note as a reflection of the Sisters’ foresight about where the city would grow.
Appointments and Patient Services
Patients can reach Mercy Hospital St. Louis at (314) 251-6000 or schedule through the First Available tool at mercy.net, with the MyMercy patient portal available for managing appointments, test results, prescriptions, and care team communication.
A campus map is available for download at mercy.net. Metro Transit St. Louis serves the Mercy campus. All rooms are private. Community education classes, maternity programs, support groups, and volunteer opportunities are also available through the hospital. Online cost estimates for services are accessible through Mercy’s price transparency tool. The hospital also includes the Thomas F. Frawley Medical Library supporting physician and co-worker research needs.
Frequently Asked Questions
What are Mercy Hospital St. Louis’s hours?
Mercy Hospital St. Louis is open 24 hours a day, 7 days a week, including the Level 1 Trauma Center and emergency department.
What is the phone number and address for Mercy Hospital St. Louis?
The main phone number for Mercy Hospital St. Louis is (314) 251-6000. The hospital is located at 615 S. New Ballas Road, St. Louis, MO 63141, at the intersection of I-270 and I-64/US 40.
What level is the Mercy Hospital St. Louis Trauma Center?
Mercy Hospital St. Louis operates St. Louis County’s only Level 1 Trauma Center, the highest possible trauma designation, staffed 24/7 by trauma surgeons and specialists.
What burn care services does Mercy Hospital St. Louis offer?
The Burn Center is the only American Burn Association and American College of Surgeons verified burn center in Missouri for both adults and children, treating burns from fire, heat, electricity, friction, and chemicals.
What maternity services does Mercy Hospital St. Louis offer?
Mercy Hospital St. Louis delivers more babies than any other hospital in St. Louis, with one in three St. Louis babies born here. Services include Mercy Birthplace, a Midwifery Birthing Center, a Level IV NICU, and the Maternal and Fetal Health Center for high-risk pregnancies.
Has Mercy Hospital St. Louis received national rankings?
Yes. U.S. News ranks it #2 in Missouri and #2 in St. Louis, with High Performing status in 21 adult procedures and conditions. Newsweek also named it among the nation’s Top 50 Best Hospitals.
What cancer services are available at Mercy Hospital St. Louis?
The David C. Pratt Cancer Center offers comprehensive outpatient cancer care with CyberKnife M6, Proton Beam Therapy, da Vinci robotic surgery, and TomoTherapy, and is Commission on Cancer accredited with commendations.
